Celebrex

What is Celebrex?

Celebrex (celecoxib) is a nonsteroidal anti-inflammatory drug (NSAID). Celecoxib works by reducing hormones that cause inflammation and pain in the body.

Celebrex is used to treat pain or inflammation caused by many conditions such as arthritis, ankylosing spondylitis, and menstrual pain. Celebrex is used to treat juvenile rheumatoid arthritis in children who are at least 2 years old.

Celebrex is also used in the treatment of hereditary polyps in the colon.

Important information

Celebrex can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Celebrex may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using Celebrex, especially in older adults. You should not take this medicine if you already have bleeding in your stomach or intestines.

Before taking this medicine

Celebrex can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Even people without heart disease or risk factors could have a stroke or heart attack while taking this medicine.

Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Celebrex may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using Celebrex, especially in older adults.

You should not use Celebrex if you are allergic to celecoxib, or if you have:
  •     bleeding in your stomach or intestines;
  •     an allergy to sulfa drugs; or
  •     a history of asthma attack or severe allergic reaction after taking aspirin or an NSAID.
To make sure Celebrex is safe for you, tell your doctor if you have:
  •     heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke;
  •     a history of heart attack, stroke, or blood clot;
  •     a history of stomach ulcers or bleeding;
  •     asthma;
  •     liver or kidney disease;
  •     fluid retention.

Taking Celebrex during the last 3 months of pregnancy may harm the unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using Celebrex.

Celecoxib can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Celebrex is not approved for use by anyone younger than 2 years old.

Celebrex side effects

Get emergency medical help if you have signs of an allergic reaction to Celebrex: sneezing, runny or stuffy nose; wheezing or trouble breathing; hives; swelling of your face, lips, tongue, or throat.

Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath.

Stop using Celebrex and call your doctor at once if you have:
  •     the first sign of any skin rash, no matter how mild;
  •     shortness of breath (even with mild exertion);
  •     swelling or rapid weight gain;
  •     signs of stomach bleeding – bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  •     liver problems – nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  •     kidney problems – little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath;
  •     low red blood cells (anemia) – pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
  •     severe skin reaction – fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common Celebrex side effects may include:
  •     stomach pain, indigestion, gas, diarrhea;
  •     swelling in your hands or feet;
  •     dizziness;
  •     rash;
  •     cold symptoms such as stuffy nose, sneezing, sore throat.